Speaker
Longjian Liu, MD, PhD, MSc (LSHTM), FAHA, Associate Professor of Epidemiology and Biostatistics at Drexel University Dornsife School of Public Health, and Adjunct Associate Research Professor of Medicine at Drexel University College of Medicine
Title
Statistics Seminar Series (Hybrid)
Subtitle
Cardiometabolic Syndrome and Risk of Heart Failure: Time-Varying Effect Modeling and Risk Prediction
Physical Location
Allen 15
Digital Location
https://msstate.webex.com/msstate/j.php?MTID=m8ce377b82dde20f05e835b18379eff44
Abstract: Cardiometabolic syndrome is a clustering of multiple risk factors for cardiovascular disease (CVD), diabetes, and CVD complications of neurodegenerative diseases. Most longitudinal epidemiological studies have examined associations between risk factors measured at a single point in time and health outcomes. However, there are many situations where the values of exposures vary over time before a health outcome occurs. In this talk, I will present why and how we apply a time-varying modeling approach to test the association between cardiometabolic syndrome and risk of incident heart failure (one of the major forms of cardiovascular diseases) using data from the Multi-Ethnic Study of Atherosclerosis. Findings from this study add new evidence to disease prevention and to the body of research literature. This analysis approach provides new insights into the study of prediction modeling of the trajectory of disease associated with time-varying exposures in large-scale longitudinal epidemiological studies.