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Computational Mathematical Biology (mentor: Dr. Xingzhou Yang)

Cilia are microscopic hair-like organelles projecting from the cell surface. Cell and flagella motilities of microorganisms are important in the studies of many complex biological systems, especially in human body. Disfunction of cilia causes varieties of clinical problems. Many ciliate microorganisms also utilize the cilia beat in the feeding, where the movement of cilia generate fluid flow to transport suspended particles or nutrient substances to the oral organism. To understand this complex biological system, we build mechanical and computational models to simulate the beating of cilia and their interaction with surrounding environments, and the numerical results will be compared with the available experimental data. The models couple the fluid dynamics and the internal force generation mechanism.

Synchrony of Beating Cilia (movie) Swimming of Chlamydomonas (movie)

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