Ciliary Dynamics and the Motilities of the Single-Celled
Chlamydomonas is a tiny
green alga with two hair-like flagella for propelling the cell body
through its fluid environment. The flagella with both
sensory and motility functions are very similar to animal cilia, which
makes Chlamydomonas an outstanding model organism to study.
In recent years, Chlamydomonas has been intensively used for
study of numerous
fundamental biological processes in cell and molecular biology,
including cilia-pathology in the human health. However the mechanism
governing the bi-flagellar
motilities is still poorly understood.
We develop a new
fluid-dynamical model, using modern
that examine swimming and a variety of the
This model couples the time-dependent
fluid dynamics and the
internal force generation mechanism
by ATP-induced molecular motor proteins.
We expect the numerical results will
validate many important biological and biomedical experiments
related to ciliary or
flagellar motilities, and advance our understanding on mechanisms
of the flagellar motilities of the complex biological systems.