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Department Colloquium

 
Speaker:
Mehdi Razzaghi
Department of Mathematics, Computer Science and Statistics
Bloomsburg University

Time and Place: Friday, November 14 at 4:00 pm, Allen 14

Title: "Analyzing Quantitative Responses from Animal Bioassay Studies"

Abstract: Animal bioassay experiments are frequently conducted to estimate the risk for humans from exposure to a toxic substance. Risk is defined as the probability of a delete- rious effect and risk assessment is the process of evaluating the probability of an adverse effect. This process has formally been defined as having four stages consisting of hazard identification, exposure assessment, dose-response assessment and risk characterization. In this presentation we first provide a brief description of the process of risk assessment and concentrate on the latter two stages of this process.

Our discussion will focus on exper- iments in which the measure of the outcome variable is quantitative. Some models that have been suggested in the literature and used in practice will be introduced. A new model based on an extension of the normal distribution will be proposed and its properties will be demonstrated. An example from a toxicological experiment will be utilized to provide further illustration.

Reception: 3:30, Allen 467
Host: Mohsen Razzaghi , (662) 325-3414, razzaghi@math.msstate.edu

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